Research infrastructure comprises all facilities and sources that promote the performance of cross-border and strategic basic research across all scientific disciplines. Besides scientific infrastructure, this includes collections, natural habitats, corpora and databases (including digital opening up).

The International Research Infrastructure (IRI) programme governing the participation in and/or funding of international research infrastructure aims to support the Flemish participation in and/or funding of international investment initiatives that are carried out at large-scale international or supranational facilities to which the Flemish Government contributes and/or whose strategic importance for Flanders can be demonstrated.